If you are currently being treated with any of the following medications, you
should not use cysteine supplements without first talking to your healthcare
Blood Pressure Medications, Angiotensin-converting Enzyme (ACE) Inhibitors
NAC may enhance the blood pressure-lowering effects of ACE
inhibitors, medications commonly used to treat high blood pressure. Examples of
ACE inhibitors include benazepril, captopril, enalapril, fosinopril, lisinopril,
moexipril, quenipril, ramepril, and trandolapril.
Treatment with NAC may enhance
the effectiveness of immunosuppressive medications such as azathioprine,
cyclophosphamide, prednisolone, or prednisone. More research in this area is
Cisplatin and Doxorubicin
Laboratory and animal studies have
suggested that NAC may reduce the toxic effects associated with both cisplatin
and doxorubicin, medications used to treat a variety of cancers. However,
scientific studies are needed to see if these effects apply to people.
Nitroglycerin and Isosorbide
Although NAC may enhance the
effectiveness of nitroglycerin and isosorbide (two medications commonly used to
treat chest pain), this combination may also increase the risk of side effects
such as severe headaches and may lead to abnormally low blood pressure.
Topical applications of NAC may increase the
effectiveness of oxiconazole, an antifungal medication used for athlete's foot.