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Table of Contents > Supplements > Potassium > Interactions
Possible Interactions with: Potassium

If you are currently being treated with any of the following medications, you should not use potassium without first talking to your healthcare provider.

Potassium levels may be increased by the following medications:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs; such as ibuprofen, piroxicam, and sulindac): This interaction is particularly likely to occur in people with decreased kidney function.
  • ACE inhibitors (such as captopril, enalapril, and lisinopril): This interaction is particularly likely to occur in people who are taking NSAIDs, potassium-sparing diuretics (such as spironolactone, triamterene, or amiloride), or salt substitutes along with the ACE inhibitor. A rise in potassium from ACE inhibitors may also be more likely in people with decreased kidney function and diabetes.
  • Heparin (used for blood clots)
  • Cyclosporine (used following a transplant to suppress the immune system)
  • Trimethoprim (an antibiotic)
  • Beta-blockers (such as metoprolol and propranolol that are used to treat high blood pressure)

Potassium levels may be decreased by the following medications:

  • Thiazide diuretics (such as hydrochlorothiazide)
  • Loop diuretics (such as furosemide and bumetanide)
  • Corticosteroids
  • Amphotericin B
  • Antacids
  • Insulin
  • Theophylline (used for asthma)
  • Laxatives

Please refer to the depletions monographs related to these medications for additional information. A healthcare practitioner will determine whether potassium supplements are needed when individuals are taking these medications.

Other potential interactions include:

  • Digoxin: Low blood levels of potassium increase the likelihood of toxic effects from digoxin, a medication used to treat abnormal heart rhythms. Normal levels of potassium should be maintained during digoxin treatment which will be measured and directed by the healthcare provider.

Drug Interactions
ACE Inhibitors
Beta-blockers
Corticosteriod Medications
Cyclosporine
Insulin
Laxatives
Loop Diuretics
Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
Theophylline-containing Medications
Thiazide Diuretics

Copyright © 2004 A.D.A.M., Inc

The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

 
RELATED INFORMATION
Potassium
  Uses of this Supplement
Asthma
Crohn's Disease
Hypertension
Osteoporosis
Stroke
Ulcerative Colitis
  Supplements with Similar Uses
View List by Use
  Drugs that Interact
Summary
ACE Inhibitors
Beta-blockers
Corticosteriod Medications
Cyclosporine
Insulin
Laxatives
Loop Diuretics
Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
Theophylline-containing Medications
Thiazide Diuretics
  Drugs that Deplete this Substance
View List
  Supplements with Similar Side Effects
View List by Side Effect
  Supplements with Similar Warnings
View List by Warning
  Learn More About
Nutrition
 

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