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Table of Contents > Supplements > Carnitine (L-Carnitine) > Interactions
Possible Interactions with: Carnitine (L-Carnitine)
Also listed as: Acetyl-L-Carnitine; L-Carnitine

If you are currently being treated with any of the following medications, you should not use carnitine without first talking to your healthcare provider.

In a laboratory study, L-carnitine supplements protected muscle tissue against toxic side effects from treatment with AZT, a medication used to treat human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). Additional studies are needed to confirm whether L-carnitine would also have this effect in people.

Treatment with L-carnitine may protect heart cells against the toxic side effects of doxorubicin, a medication used to treat cancer, without reducing the effectiveness of this chemotherapy agent.

Isotretinoin, a strong medication used for severe acne, can cause abnormalities in liver function, measured by a blood test, as well as elevations in cholesterol and muscle pain and weakness. These symptoms are similar to those seen with carnitine deficiency. Researchers in Greece showed that a large group of people who had side effects from isotretinoin got better when taking L-carnitine compared to those who took a placebo.

Valproic Acid
The anticonvulsant medication valproic acid may lower blood levels of carnitine and can cause carnitine deficiency. Taking L-carnitine supplements may prevent deficiency and may also reduce the side effects of valproic acid.

Drug Interactions
Valproic Acid and Derivatives

Copyright © 2004 A.D.A.M., Inc

The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

Carnitine (L-Carnitine)
  Uses of this Supplement
Alzheimer's Disease
Anorexia Nervosa
Chronic Fatigue Syndrome
Congestive Heart Failure
  Supplements with Similar Uses
View List by Use
  Drugs that Interact
Valproic Acid and Derivatives
  Drugs that Deplete this Substance
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View List by Side Effect
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