Richard's Whole Foods  
10% Off Register online today and receive 10% off your next in-store purchase.
Your E-mail:     
Healthy Recipes Reference Library Store Specials About Us Friday, May 05, 2006
Search Site
Departments
Reference Library
  
Sign In
My Account
Contact Us
Shopping Cart
Checkout
Help


 
 
Table of Contents > Herbs > Milk Thistle > Interactions
Possible Interactions with: Milk Thistle
Also listed as: Silybum marianum; St. Mary's Thistle
 

If you are currently being treated with any of the following medications, you should not use milk thistle without first talking to your healthcare provider.

Similar to its ability to protect against damage to the liver from alcohol and acetominophen, as discussed in the Overview, milk thistle may also protect against liver damage from the following medications:

  • Antipsychotics: This group of medications used for schizophrenia includes butyrophenones (such as haloperidol) and phenothiazines (such as chlorpromazine, fluphenazine, and promethazine)
  • Phenytoin: a medication used for seizures
  • Halothane: a medication used during general anesthesia

Other medications that may interact with milk thistle include:

Aspirin
One animal study found that milk thistle may enhance the effectiveness of aspirin in rats with liver cirrhosis. Whether this herb-drug combination has the same effect in people is not known at this time.

Chemotherapy medications
Preliminary research suggests that silybin may enhance the tumor fighting effects of cisplatin and doxorubicin when tested against breast and ovarian cancer cells.

In addition, milk thistle may protect the kidneys against toxic side effects associated with cisplatin and cyclosporine, two medications that are commonly used to treat cancer.

On the other hand, a different laboratory study revealed that the anticancer effect of cisplatin and ifosfamide was diminished in the presence of milk thistle. More research needs to be done to assess how milk thistle and cancer-fighting agents interact.


Drug Interactions
Acetaminophen-containing Medications
Antipsychotic Medications
Aspirin
Cyclosporine
Doxorubicin
Phenytoin-containing Medications

Copyright © 2004 A.D.A.M., Inc

The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

 
RELATED INFORMATION
Milk Thistle
  Uses of this Herb
Alcoholism
Breast Cancer
Cervical Dysplasia
Cirrhosis
Hepatitis, Viral
Hypercholesterolemia
Prostate Cancer
  Herbs with Similar Uses
View List by Use
  Drugs that Interact
Summary
Acetaminophen-containing Medications
Antipsychotic Medications
Aspirin
Cyclosporine
Doxorubicin
Phenytoin-containing Medications
  Herbs with Similar Side Effects
View List by Side Effect
  Herbs with Similar Warnings
View List by Warning
  Learn More About
Herbal Medicine
 

Home | Store Locations | Buy Online | Store Specials | About Us | Delicious Living | Reference Library | News & Features | Health Tools | Treatment Options | Healthy Recipes | Ingredient Glossary | My Account | Contact Us | Help | Shopping Cart | Privacy Policy | Terms of Use |



Powered By Living Naturally