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Table of Contents > Drugs >  Zafirlukast
Zafirlukast
Pronunciation
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(za FIR loo kast)

Brand Names
Accolate®

Therapeutic Categories
Leukotriene Receptor Antagonist

Reasons not to take this medicine

  • If you have an allergy to zafirlukast or any other part of the medicine.


What is this medicine used for?

  • This medicine is used in the prevention and long-term treatment of asthma. It is not for the immediate (urgent) treatment of an asthma attack.


How does it work?

  • Zafirlukast decreases the body's production of a group of chemicals called leukotrienes that worsen asthma.


How is it best taken?

  • Take on an empty stomach. Take 1 hour before or 2 hours after meals.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop taking medicine without talking with healthcare provider.


What are the precautions when taking this medicine?

  • Check medicines with healthcare provider. This medicine may not mix well with other medicines. Erythromycin and theophylline may decrease medicine's effect.
  • Wear disease medical alert identification for asthma.
  • Use caution with aspirin and aspirin-containing products. Side effects of these medicines may be increased.
  • If you are on warfarin (blood thinner) you will require more frequent monitoring if this medicine is added.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Do not use if you are breast-feeding.


What are the common side effects of this medicine?

  • Headache. Mild pain medicine may help.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Diarrhea.
  • Belly pain and cramps.
  • Rarely, liver disease may occur.


What should I monitor?

  • Check prothrombin time/INR if you are on warfarin. Talk with healthcare provider.
  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Severe nausea, vomiting, and/or diarrhea.
  • Nausea, vomiting, belly pain, itchy, flu-like feeling, feeling tired, dark urine, yellow eyes or skin, not hungry.
  • Any rash.
  • No improvement in condition or feeling worse.


How should I store this medicine?

  • Store in the original container at room temperature. Protect from light and moisture.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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