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Table of Contents > Drugs >  Rosiglitazone
Rosiglitazone
Pronunciation
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(roe si GLI ta zone)

Brand Names
Avandia®

Therapeutic Categories
Antidiabetic Agent (Thiazolidinedione)

Reasons not to take this medicine

  • If you have an allergy to rosiglitazone or any other part of the medicine.
  • If you have active liver disease or yellowing (jaundice) during troglitazone therapy.
  • If you have type 1 diabetes or an acid condition of the blood called diabetic ketoacidosis.


What is this medicine used for?

  • This medicine lowers blood sugar in type 2 diabetics. It can be used alone or in combination with other diabetes medicine. It may take up to 3 months to see the full effect.


How does it work?

  • Rosiglitazone increases insulin activity in the body.


How is it best taken?

  • Take with or without food. Take with food if this medicine causes an upset stomach.
  • Take at a similar time every day.
  • Follow diet plan and exercise program as recommended by healthcare provider.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is missed at the usual meal, take it with the next meal.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • Wear disease medical alert identification for diabetes.
  • Do not use if you have liver disease. Talk with healthcare provider.
  • Use caution if you have high cholesterol (increases bad cholesterol). Talk with healthcare provider.
  • Use caution if you have a weakened heart. May cause water weight gain. Talk with healthcare provider.
  • During times of stress such as infection, trauma, or surgery your medicine requirements may change. Talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • This medicine can cause ovulation in premenopausal women who have not been ovulating. Birth control may need to be considered. Pregnancy can occur.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Weight gain caused by swelling.
  • Increased cholesterol (increase of 10% to 15%).
  • Cough, cold, redness and swelling of the sinuses.
  • Headache.
  • Back pain.
  • Rare, but serious liver injury.


What should I monitor?

  • Check blood sugar as ordered by healthcare provider. Call if glucose is less than 80 mg/dL or greater than 250 mg/dL. Bring results to follow-up visits.
  • Watch for low blood sugar. This can cause anger, shaking, rapid heartbeats, confusion, sweating.
  • Watch for high blood sugar. Causes many trips to the bathroom, thirst, and weight loss.
  • Check blood work. Talk with healthcare provider.
  • Follow diet plan and exercise program as recommended by healthcare provider.
  • Have an eye exam and visit to the foot doctor every year.
  • Liver function tests need monitoring before therapy and then every 2 months for the first year and periodically after that. Talk with healthcare provider.
  • Check lipid (cholesterol) panel. Talk with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Low blood sugar or very high blood sugar.
  • Nausea, vomiting, belly pain, feeling tired, dark urine, yellow eyes/skin, not hungry.
  • For women, a change in monthly period.
  • Any rash.


How should I store this medicine?

  • Store in a tight container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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