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Table of Contents > Drugs >  Quinapril and Hydrochlorothiazide
Quinapril and Hydrochlorothiazide
Pronunciation
Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(KWIN a pril & hye droe klor oh THYE a zide)

Brand Names
Accuretic™

Therapeutic Categories
Angiotensin-Converting Enzyme (ACE) Inhibitors; Diuretic, Thiazide

What key warnings should I know about before taking this medicine?

  • Do not use this medicine if you are pregnant. Use during the second and third trimester (more than 12 weeks pregnant) can cause harm to the baby you are carrying. Call healthcare provider right away if you become pregnant. Your medicine will need to be changed.


Reasons not to take this medicine

  • If you have an allergy to another thiazide, sulfonamide drugs, hydrochlorothiazide, quinapril, or any other part of the medicine. If you are allergic to another angiotensin converting enzyme inhibitor, talk with healthcare provider.
  • If you have any of the following conditions: Disease of the vessels (arteries) that take blood to the kidney, primary hyperaldosteronism, idiopathic or hereditary angioedema.
  • If you are more than 12 weeks pregnant.


What is this medicine used for?

  • This medicine is used to treat high blood pressure.


How does it work?

  • Quinapril lowers blood pressure by decreasing production of a strong chemical in the body that increases blood pressure.


How is it best taken?

  • Take with or without food. Take with food if this medicine causes an upset stomach.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • Do not use over-the-counter products which may affect blood pressure (eg, cough/cold remedies, diet pills, stimulants, ibuprofen or like products, certain herbal products and supplements). Talk with healthcare provider.
  • Avoid potassium-containing salt substitutes or potassium supplements. Talk with healthcare provider.
  • Caution in hot weather. You may see a greater blood pressure lowering effect.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Do not use in pregnancy and do not get pregnant. Use birth control that you can trust while taking this medicine.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Dizziness is common. Rise slowly over several minutes from sitting or lying position. Be careful climbing stairs.
  • Feeling lightheaded or tired. Avoid driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
  • Abnormal (metallic, salty, or none). This is usually reversible.
  • Dry cough.
  • Dry mouth. Frequent mouth care, sucking hard candy, or chewing gum may help.


What should I monitor?

  • Check blood pressure regularly.
  • Follow diet plan and exercise program as recommended by healthcare provider.
  • Check blood work. Talk with healthcare provider.
  • If you are diabetic, check blood sugar as ordered by healthcare provider.
  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, throat.
  • Passing out, fainting, dizziness, or lightheadedness.
  • Excessive perspiration, dehydration, vomiting/diarrhea. May lead to low blood pressure.
  • Significant, persistent cough.
  • Signs of low potassium. Low potassium may make you feel tired, weak, or have numbness, tingling, muscle cramps, constipation, vomiting or rapid heartbeats. Can lead to serious heartbeat problems.
  • Any rash.


How should I store this medicine?

  • Store in tight, light-resistant container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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