Ketorolac Tromethamine
   

Ketorolac Tromethamine
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(KEE toe role ak troe METH a meen)

Brand Names
Acular® Ophthalmic; Toradol® Injection; Toradol® Oral

Foreign Brand Names
Dolac Inyectable (Mexico); Dolac Oral (Mexico)

Therapeutic Categories
Nonsteroidal Anti-Inflammatory Agent (NSAID)

What key warnings should I know about before taking this medicine?

  • This medicine is only to be used for 5 days total. It is for serious, short-term pain. It may cause severe side effects if taken for longer. Let your healthcare provider know if you have any of these problems: Ulcer disease in the stomach or intestines, severe kidney disease, a risk of bleeding or any active bleeding, allergies to ketorolac, aspirin, or any other pain medicine. Do not take this medicine if you are pregnant or breast-feeding. Tell your healthcare provider if you are 65 years of age or older or weigh less than 110 pounds.


Reasons not to take this medicine

  • If you have an allergy to aspirin, another nonsteroidal anti-inflammatory drug (NSAID), ketorolac, or any other part of the medicine. A few examples of NSAIDs are ibuprofen, naproxen, diclofenac, nabumetone, and ketoprofen.
  • If you have any of the following conditions: Nasal polyps, ulcer disease, recent bleeding in the gastrointestinal tract, a hole in the gastrointestinal tract, severe kidney disease, risk of kidney failure, use before major surgery, bleeding problems, bleeding in the brain.
  • If you are pregnant and in labor.
  • If you are breast-feeding.
  • If you are taking any of these medicines: Aspirin, probenecid, or another nonsteroidal anti-inflammatory drug.


What is this medicine used for?

  • This medicine is used for short-term (up to 5 days) treatment of moderately severe pain.
  • The eye solution is used to relieve itching caused by seasonal allergic conjunctivitis. It is also used to treat postoperative inflammation following cataract extraction.


How does it work?

  • Ketorolac tromethamine reduces inflammation and pain by blocking production and release of chemicals that produce it.


How is it best taken?

  • Oral:
    • Take with or without food. Take with food if this medicine causes an upset stomach.
  • Eye:
    • For the eye only.
    • Take out soft contact lenses before using medicine. Lenses can be replaced 15 minutes after medicine is given.
    • Do not touch the bottle or tube tip to the eye, lid, or other skin.
    • Tilt head back and drop medicine into eye.
    • After using medicine keep your eyes closed. Apply pressure to the inside corner of the eye. Do this for 3-5 minutes. This keeps medicine in the eye.
    • Separate each eye medicine by 5 minutes. Give one and wait 5 minutes before using the next.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.


What are the precautions when taking this medicine?

  • Oral:
    • Do not use this medicine for more than 5 days.
    • If you are 65 or older or weight less than 110 pound, use this medicine with caution. Can cause severe side effects. You will need a smaller dose.
    • Avoid alcohol (includes wine, beer, and liquor). Can cause increases in stomach irritation.
    • If you have had a stomach ulcer or bleeding, tell healthcare provider.
    • Use caution if you have kidney disease. Talk with healthcare provider. You will need a smaller dose.
    • Use caution if you have a weakened heart. May cause increased shortness of breath or weight gain. Talk with healthcare provider.
    • Use caution if you have high blood pressure. Your blood pressure may increase. Talk with healthcare provider.
    • You will have a tendency to bleed more easily. Tell dentists, surgeons, and other healthcare providers about this medicine. You may be instructed to stop this medication for a while before any procedure. Ask for specific instructions about the time for stopping and restarting.
    • Avoid aspirin, aspirin-containing products, other pain medicines, other blood thinners (warfarin, ticlopidine, clopidogrel), garlic, ginseng, ginkgo, and vitamin E while taking this medicine. Talk with healthcare provider.
  • All forms:
    • Tell healthcare provider if you are allergic to any medicine, especially aspirin. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
    • Do not use if you are pregnant or nursing.
    • Tell healthcare provider if you plan on getting pregnant.


What are the common side effects of this medicine?

  • Feeling sleepy, dizzy, or unable to think clearly. Avoid driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
  • Headache. Mild pain medicine may help.
  • Belly pain, heartburn, cramps, diarrhea, gas.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Stomach bleeding or ulceration. Watch stools for dark, tarry black color. Talk with healthcare provider.
  • Eye: Irritation, allergic reactions.


What should I monitor?

  • Relief of symptoms. Are they better, worse, or about the same?
  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Severe nausea, vomiting, and/or diarrhea.
  • Blood in the stool and toilet bowl, vomiting blood, or coughing up blood.
  • Unusual bruising or bleeding.
  • Serious eye pain or redness.
  • Any rash.
  • No improvement in condition or feeling worse.


How should I store this medicine?

  • Store in a tight, light-resistant container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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