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Table of Contents > Drugs >  Pioglitazone
Pioglitazone
Pronunciation
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(pye oh GLI ta zone)

Brand Names
Actos™

Therapeutic Categories
Antidiabetic Agent (Thiazolidinedione)

Reasons not to take this medicine

  • If you have an allergy to pioglitazone or any other part of the medicine.
  • If you have active liver disease or yellowing (jaundice) during troglitazone therapy.


What is this medicine used for?

  • This medicine lowers blood sugar in type 2 diabetics. It can be used alone or in combination with other diabetic medicines.


How does it work?

  • Pioglitazone increases insulin activity in the body.


How is it best taken?

  • Take with or without food. Take with food if this medicine causes an upset stomach.
  • Take at a similar time everyday.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • Do not use if you have liver disease. Talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Birth control pills may not work. Use another form of birth control while taking this medicine.
  • Do not use if you are breast-feeding.


What are the common side effects of this medicine?

  • Weight gain. Could be on the average of 1-6 pounds.
  • Swelling.
  • Headache. Mild pain medicine may help.
  • May cause ovulation in women who have not being ovulating. If this occurs then there is a risk of pregnancy if sexually active.


What should I monitor?

  • Check blood sugar as directed by healthcare provider. Low blood sugar causes irritable, shaking, rapid heartbeats, confusion, and sweating. High blood sugar causes frequent urination, thirst, and weight loss.
  • Periodic blood work required. Liver function tests are needed before therapy and then every 2 months for the first year. Talk with healthcare provider.
  • Follow diet plan and exercise program as recommended by healthcare provider.
  • Have an eye exam and visit to the foot doctor every year.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Low blood sugar or very high blood sugar.
  • Fever or signs of infection.
  • Nausea, vomiting, abdominal pain, fatigue, dark urine, yellow eyes or skin, not hungry.
  • Any rash.


How should I store this medicine?

  • Store in a tight container at room temperature. Protect from moisture and humidity.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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