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Table of Contents > Drugs >  Neomycin, Polymyxin B, and ...
Neomycin, Polymyxin B, and Dexamethasone
Pronunciation
Brand Names
Therapeutic Categories
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(nee oh MYE sin, pol i MIKS in bee, & deks a METH a sone)

Brand Names
AK-Trol®; Dexacidin®; Dexasporin®; Maxitrol®

Therapeutic Categories
Antibiotic/Corticosteroid, Ophthalmic

What is this medicine used for?

  • Neomycin and polymixin B are antibiotics used to treat a variety of bacterial infections.
  • Dexamethasone is used to reduce redness, irritation, swelling, and itching.
  • The eye drops are used in steroid-responsive inflammatory eye conditions in which hydrocortisone is indicated and where bacterial infection or a risk of bacterial infection exists.


How does it work?

  • Neomycin inhibits metabolic activities in the bacteria.
  • Polymixin B makes some of the manufacturing cells in the bacteria leaky.
  • Dexamethasone prevents/reduces irritation and swelling.


How is it best taken?

  • For the eye only. Shake suspension well first.
  • Wash your hands before and after use.
  • Suspension:
    • Tilt your head back and drop medicine into your eye.
    • Avoid touching the dropper to your eye, lid, or other skin.
    • Separate each eye medicine by 5 minutes. Give one and wait 5 minutes before using the next.
    • Close eye and hold pressure on corner of eye closest to nose for 1 minute.
  • Ointment:
    • Place medicine inside the lower lid. Close the eye for 1-2 minutes. Roll eyeball around.
    • Separate each eye medicine by 10 minutes. Give one and wait 10 minutes before using the next.


What do I do if I miss a dose?

  • Apply a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not apply a double dose or extra doses.


What are the precautions when taking this medicine?

  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Bright lights may be irritating. Keep sunglasses with you.
  • Blurred vision. Use caution when driving, or doing tasks that need clear vision.
  • Stinging after putting drops in eye.


What should I monitor?

  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Any rash.
  • No improvement in condition or feeling worse.


How should I store this medicine?

  • Store at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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