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Table of Contents > Drugs >  Naratriptan
Naratriptan
Pronunciation
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(NAR a trip tan)

Brand Names
Amerge®

Therapeutic Categories
Serotonin 5-HT1D Receptor Agonist

Reasons not to take this medicine

  • If you have an allergy to naratriptan or any other part of the medicine.
  • If you have any of the following conditions: Ischemic bowel disease, coronary artery disease or risk factors for coronary disease (male, high cholesterol, diabetes, overweight, smoking, positive family history), heart attack, poorly controlled high blood pressure, severe kidney disease, severe liver disease.
  • If you have taken another serotonin antagonist (rizatriptan, sumatriptan, zolmitriptan) or ergotamine-containing product within the past 24 hours.


What is this medicine used for?

  • This medicine is used to get rid of or decrease the pain and symptoms of a migraine headache. It is not used to prevent future attacks.
  • It may take 1-3 hours to feel the full benefits of this medicine.


How does it work?

  • Naratriptan works by squeezing certain blood vessels in the brain and preventing irritation/inflammation.


How is it best taken?

  • Swallow tablet whole. Do not chew, break, or crush.
  • Take with liquids as early as possible after the attack has started.
  • If no headache relief by 4 hours after the first dose, then take another dose.
  • Do not take more than 5 mg as a total daily dose.
  • Do not take within 24 hours of other migraine medication without consulting healthcare provider.


What do I do if I miss a dose?

  • This medicine is taken on an as needed basis, not on a regularly scheduled one. It can be taken any time during the course of the headache, but sooner is better.


What are the precautions when taking this medicine?

  • Avoid alcohol (includes wine, beer, and liquor). Can worsen headache.
  • Do not take if you have a history of angina (chest pain from the heart), heart spasms, heart attack, or uncontrolled high blood pressure.
  • Do not take within 24 hours of other headache medicines. Talk with healthcare provider.
  • Tell healthcare provider if you are taking any medicines for depression, like monoamine oxidase inhibitors. These include isocarboxazid, phenelzine, and tranylcypromine. Certain medicines do not mix well with this medicine.
  • Use caution if you have risk factors for heart disease (high blood pressure, high cholesterol, overweight, diabetes, cigarette smoking, a male >40 years of age, other family members with heart disease, postmenopausal women). Talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Feeling sleepy, lightheaded, or dizzy. Avoid driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Numbness or tingling of hands or feet.


What should I monitor?

  • Return of headache. Talk with healthcare provider if it changes from usual course or if it does not get better with this medicine.


Reasons to call healthcare provider immediately

  • No relief of headache after treatment.
  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Chest pain, tightness, or heaviness, throat pain or tightness, rapid heartbeat, or difficult breathing.
  • Too tired or sleepy.
  • Passing out, fainting, dizziness, or lightheadedness.
  • Any rash.


How should I store this medicine?

  • Store in a tight, light-resistant container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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