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Table of Contents > Drugs >  Flucytosine
Flucytosine
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(floo SYE toe seen)

Brand Names
Ancobon®

Foreign Brand Names
Ancotil® (Canada)

Therapeutic Categories
Antifungal Agent, Oral

What key warnings should I know about before taking this medicine?

  • Your healthcare provider must closely monitor your blood cells, kidney and liver function.


Reasons not to take this medicine

  • If you have an allergy to flucytosine or any other part of the medicine.


What is this medicine used for?

  • This medicine is used to treat serious infections. These infections are caused by fungus (yeasts). Flucytosine is used with another antibiotic to treat meningitis.


How does it work?

  • Flucytosine changes protein production of the fungus (yeast). It also affects genetic coding.


How is it best taken?

  • Take with food to avoid nausea. Take a few capsules at a time over 15 minutes.
  • A liquid is available if you cannot swallow pills. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.
  • Use entire prescription as directed, even if feeling better.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • Use caution if you have in kidney disease. Talk with healthcare provider.
  • You will bleed easily. Be careful. Avoid injury.
  • Avoid aspirin, aspirin-containing products, ibuprofen or like products, other blood thinners (warfarin, ticlopidine, clopidogrel), garlic, ginseng, ginkgo, vitamin E.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Do not use if you are breast-feeding.


What are the common side effects of this medicine?

  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Belly pain, cramps, not hungry, or diarrhea.
  • Risk of infection. Avoid crowds and people with infections, colds, or flu.


What should I monitor?

  • Check blood work. Talk with healthcare provider.
  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Severe nausea, vomiting, or diarrhea.
  • Changes in thinking clearly and logically.
  • Decrease in amount of urine or trips to the bathroom.
  • Signs of another infection.
  • Severe belly pain, feeling tired, dark urine, yellow eyes or skin, and not hungry.
  • Any rash.


How should I store this medicine?

  • Store capsules in a tight, light-resistant container at room temperature.
  • If you are storing liquid in the refrigerator, throw away after 70 days.
  • If you are storing liquid at room temperature, throw away after 14 days.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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