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Table of Contents > Drugs >  Atovaquone and Proguanil
Atovaquone and Proguanil
Pronunciation
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(a TOE va kwone & pro GWA nil)

Brand Names
Malarone™

Therapeutic Categories
Antimalarial Agent

Reasons not to take this medicine

  • If you have an allergy to atovaquone, proguanil, or any other part of the medicine.


What is this medicine used for?

  • This medicine is used for prevention or treatment of malaria.


How does it work?

  • Both these drugs prevent the parasite that causes malaria from reproducing.


How is it best taken?

  • Take with food or a milk drink.
  • Take at a similar time everyday.
  • If you vomit within an hour of taking the medicine then take another dose.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • Use additional measures for malarial prevention. Wear protective clothing and insect repellents. Use bed nets.
  • Use caution if you have kidney disease. Talk with healthcare provider.
  • Avoid tetracycline, metoclopramide and rifampin if taking this medicine.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Pregnant women traveling to areas where malaria is of concern should discuss the risks with a healthcare provider first.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Active treatment produces more side effects than preventative treatment.
  • Belly pain.
  • Nausea. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Vomiting.
  • Headache.
  • Diarrhea.
  • Weakness and dizziness.


What should I monitor?

  • Watch for change in temperature.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, throat.
  • Any fever that occurs during or after return from the malaria area.
  • Severe vomiting or diarrhea.
  • Any rash.
  • If using to treat maleria and there is no improvement in condition or feeling worse.


How should I store this medicine?

  • Store at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets. Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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